Toggle menu
+31 20 808 0893

Rabbit pAb Anti-ATP7A Antibody | Gentaur

€340.00
(No reviews yet) Write a Review
SKU:
544-MBS9608825-GEN
Availability:
IN STOCK
Size:
100 µL
Adding to cart… category.add_cart_announcement

Product Description

Rabbit pAb Anti-ATP7A Antibody

Species Reactivity

 Human, Mouse, Rat

Published species

 Human

Host/Isotype

 Mouse / IgG2b

Class

 Monoclonal

Type

 Antibody

Clone

 S60-4

Immunogen

 Synthetic peptide amino acids 42-61 (cytoplasmic C-terminus) of human Copper- transporting ATPase1
View antigen

Conjugate

 Unconjugated

Form

 Liquid

Concentration

 1 mg/mL

Purification

 Protein G

Storage buffer

 PBS, pH 7.4, with 50% glycerol

Contains

 0.09% sodium azide

Storage conditions

 -20°C

RRID

 AB_2735125

Target Information

ATP7A (also known as Copper-transporting ATPase 1) functions as a transmembrane copper-translocating P-type ATPase and plays a vital role in systemic copper absorption in the gut and copper reabsorption in the kidney.

Polarized epithelial cells such as Madin-Darby canine kidney cells are a physiologically relevant model for systemic copper absorption and reabsorption in vivo.

Although ATP7A is not detectable in most normal tissues, it is expressed in a considerable fraction of many common tumor types. Increased expression of ATP7A renders cells resistant to cisplatin and carboplatin. Mutations in the ATP7A gene result in Menkes disease, which is fatal in early childhood.

Product Videos

Custom Field

Size 100 µL

Product Reviews

Write a Review