Molecular Class-Specific Information System (MCSIS) project

18th Dec 2021

Available MCSIS

The GPCRDB: a Molecular-Specific Information System for G Protein-Coupled Receptors (created in 1994)

The GPCRDB at the CMBI, the Netherlands

The NucleaRDB: a Molecular-Specific Information System for Nuclear Receptors (created in April 2000)

The NucleaRDB at the CMBI, the Netherlands

Mirror site at UCSF, USA (no longer available)

The PrionDB: a Molecular-Specific Information System for Prion proteins (created July, 21 2003)

The PrionDB at the CMBI, the Netherlands

Mirror site at UCSF, USA (no longer available)

The KChannelDB: a Molecular-Specific Information System for potassium channels (created July, 25 2003)

The KChannelDB at the CMBI, the Netherlands

Mirror site at UCSF, USA 

The GPCRIPDB: a Molecular-Specific Information System for GPCR Interacting Partners (G proteins & RAMPs) (created May, 23 2005)

The GPCRIPDB at the CMBI, the Netherlands

The MCSIS methodology

Visit this site to get some information on the MCSIS methodology.

People

CMBI, The Netherlands:

Gerrit Vriend

Emmanuel Bettler, Simon Folkertsma, Joost Van Durme

Wim Janssen, Maarten Hekkelman

UCSF, USA:

Fred E. Cohen

Cédric Govaerts, Anthony Lau, Barnaby May, Lawrence Lee, Delphine Bichet

Erik Ellestad

Virtual Biology Lab, University of Nice, France:

Florence Horn

Other partners listed here as well 

  •  AARSDB -http://rose.man.pozman.pl/aars/index.html
  • Aminoacyl-tRNA synthetase database.

  • ASPD -http://wwwmgs.bionet.nsc.ru/mgs/gnw/aspd/
  • Artificial selected proteins/peptides database.

  • BacTregulators -http://www.bactregulators.org/
  • Transcriptional regulators of AraC and TetR families.

  • CSDBase -http://www.chemie.uni-marburg.de/~csdbase/
  • Cold shock domain-containing proteins.

  • CuticleDB -http://bioinformatics.biol.uoa.gr/cuticleDB
  • Structural proteins of Arthropod cuticle.

  • DCCP -http://sdbi.sdut.edu.cn/DCCP/en/index.php
  • Database of copper-chelating proteins.

  • DExH/D Family Database -http://www.helicase.net/dexhd/dbhome.htm
  • DEAD-box, DEAH-box and DExH-box proteins.

  • Endogenous GPCR List -http://www.tumor-gene.org/GPCR/gpcr.html
  • G protein-coupled receptors database.

  • EROP-Moscow -http://erop.inbi.ras.ru
  • Endogenous regulatory oligopeptide database.

  • ESTHER -http://www.ensam.inra.fr/esther
  • Estrase and other alpha/beta hydrolase enzmymes.

  • GPCRDB -http://www.gpcr.org/7tm/
  • G protein-coupled receptors database.

  • gpDB -http://bioinformatics.biol.uoa.gr/gpDB
  • G-proteins and their interaction with GPCRs.

  • Histone Database -http://research.nhgri.nih.gov/histones/
  • Histone fold sequence and structures.

  • Homeobox Page -http://www.biosci.ki.se/groups/tbu/homeo.html
  • Homeobox proteins, classification and evolution.

  • Hox-Pro -http://www.iephb.nw.ru/labs/lab38/spirov/hox_pro/hox-pro00.html
  • Homeobox genes database.

  • Homeodomain Resource -http://research.nhgri.nih.gov/homeodomain/
  • Homeodomain sequence, structures and related genetic and genomic information.

  • HORDE -http://bioinfo.weizmann.ac.it/HORDE
  • Human olfactory receptor data exploratorium.

  • InBase -http://www.neb.com/neb/inteins.html
  • Inteins (protein splcing elements) database: proteins, sequence, bibliography.

  • KinG - Kinase in Genomes -http://hodkin.mbu.iisc.ernet.in/~king
  • S/T/Y- Specific protein kinase encoded in complete genomes.

  • Knottins -http://knnottin.cbs.cnrs.fr
  • Database of Knottins - small proteins with an unusual "disulphide through disulphide" knot..

  • LGICdb -http://www.pasture.fr/recherche/banques/LGIC/LGIC.html
  • Ligand-gated ion channel subunit sequences database.

  • Lipase Engineering Database -http://www.led.uni-stuttgart.de/
  • Sequence, structure and function of lipase and estrases.

  • LOX-DB -http://www.dkfz-heidelberg.de/spec/lox-db/
  • Mammalian, invertebrate, plant and fungal lipoxygenases.

  • MEROPS -http://merops.sanger.ac.uk/
  • Database of proteolytic enzymes (peptidases).

  • NPD -http://npd.hgu.mrc.ac.uk/
  • Nuclear protein database.

  • NuclearRDB -http://www.receptors.org/NR/
  • Nuclear receptor superfamily.

  • Nuclear Receptor Resource -http://nrr.georgetown.edu/NRR/nrrhome.html
  • Nuclear receptor superfamily.

  • NUREBASE -http://www.ens-lyon.fr/LBMC/laudet/nurebase.html
  • Nuclear hormone receptors database.

  • Olfactory Recptor Database -http://senselab.med.yale.edu/senselab/ordb/
  • Sequences for olfactory receptor-like molecules.

  • ooTFD -http://www.ifti.org/ootfd
  • Object-oriented transcription factors database.

  • PKR -http://pkr.sdsc.edu/html/index.shtml
  • Prtoein kinase resource: sequence, enzymology, genetics and molecular and structural properties.

  • PLPMDB -http://www.studiofmp.com/plpmdb/
  • Pyridoxal-5'-phosphate dependent enzymes mutation.

  • ProLysED -http://genome.ukm.my/prolyses
  • A database of bacterial protease systems.

  • Prolysis -http://delphi.phys.univ-tours.fr/Prolysis/
  • Protease and natural and synthetic protease inhibitors.

  • REBASE -http://rebase.neb.com/rebase/rebase.html
  • Restriction enzyme and associated methylases.

  • Ribonuclease P Database -http://www.mbio.ncsu.edu/RNaseP/home.html
  • RNase P Sequences, alignments and structures.

  • RPG -http://ribosome.miyazaki-med.ac.jp/
  • Ribosomal protein gene database.

  • RTKdb -http://pbil.univ-lyon1.fr/RTKdb
  • Receptor tyrosine kinase sequences.

  • RNRdb -http://rnrdb.molbio.su.se/
  • Ribonucleotide reductase database.

  • S/MARt db -http://smartdb.bioinf.med.uni-goettingen.de/
  • Nuclear scaffold/matrix attached regions.

  • Scorpion -http://research.i2r.a-star.edu.sg:8080/scorpion/
  • Database of scorpion toxins.

  • SDAP -http://fermi.utmb.edu/SDAP
  • Structural database of allergenic proteins and food allergens.

  • SENTRA -http://compbio.mcs.anl.gov/sentra/
  • Sensory signal transduction proteins.

  • SEVENS -http://sevens.cbrc.jp/
  • 7-transmembrane helix receptors (G-protein coupled).

  • SRPDB -http://bio.lundberg.gu.se/dbs/SRPDB/SRPDB.html
  • Proteins of the signal recognition particles.

  • TrSDB -http://bioinf.uab.es/cgi-bin/trsdb/trsdb.pl
  • Transcription factor database.

  • VKCDB -http://vkcdb.biology.ualberta.ca/
  • Voltage-gated potassium channel database.

  • WntDatabase -http://www.stanford.edu/~musse/wntwindow.html
  • Wnt proteins and phenotypes.