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Mouse Anti-citrullinated fibrinogen | Gentaur

€340.00
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SKU:
604-MQ13.102-100-GEN
Availability:
IN STOCK
Size:
100 µL
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Product Description

Mouse Anti-citrullinated fibrinogen

Specifications
 
Applications IHC, WB, ELISA
 
Host Mouse
 
Clonality Monoclonal
 
Clone 20B2
 
Supplier MONOSAN
 
Shipping & storage Shipping condition
 
Blue Ice
 
Storage temperature2-8°C
 
We studied the diagnostic performance of the anti-human citrullinated fibrinogen antibody (AhFibA) ELISA for rheumatoid arthritis (RA) in a consecutive cohort (population 1) and evaluated the agreement between the AhFibA ELISA and four other assays for anti-citrullinated protein/peptide antibodies (ACPAs) as well as rheumatoid factor in patients with longstanding RA (population 2).
 
Population 1 consisted of 1024 patients with rheumatic symptoms; serum samples from these patients were sent to our laboratory for ACPA testing within the context of a diagnostic investigation for RA.
 
Ninety-two of these patients were classified as having RA according to the American College of Rheumatology criteria and 463 were classified as non-RA patients. Population 2 consisted of 180 patients with longstanding RA and was used to assess agreement and correlations between five ACPA assays.
 
Anti-cyclic citrullinated peptide (CCP)1 and anti-CCP2 antibodies were detected using a commercially available ELISA, AhFibA using ELISA, and anti-PepA and anti-PepB antibodies using line immunoassay. Applying previously proposed cut-offs for AhFibA, we obtained a sensitivity of 60.9% and a specificity of 98.7% in population 1.

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